Macula densa cells are located in the distal convoluted tubule and they can sense when levels of sodium and chloride are low.
致密斑位于远曲小管，可以感受到钠和氯水平降低。
Macula densa
原声例句
Osmosis-解剖与生理
Osmosis-解剖与生理
The extraglomerular mesangial cells help with the signalling between macula densa cells and juxtaglomerular cells.
球外系膜细胞辅助致密斑和球旁细胞的信息传递过程。
Osmosis-解剖与生理
So, in the case of hypovolemia and hypotension, the macula densa cells sense the low sodium and chloride levels and send a signal over to the juxtaglomerular cells which are located in the wall of the afferent arteriole.
因此，当血容量减少、低血压时，致密斑感受到钠、氯含量降低，传递信号给位于入球小动脉血管壁上的球旁细胞。
英语百科
Macula densa
In the kidney, the macula densa is an area of closely packed specialized cells lining the wall of the cortical thick ascending limb, at the transition to the distal convoluted tubule.
The cells of the macula densa are sensitive to the concentration of sodium chloride in the late thick ascending limb. A decrease in sodium chloride concentration initiates a signal from the macula densa that has two effects: (1) it decreases resistance to blood flow in the afferent arterioles via vasodilation, which increases glomerular capillary hydrostatic pressure and helps increase the glomerulus filtration rate (GFR) toward normal, and (2) it increases renin release from the juxtaglomerular cells of the afferent and efferent arterioles, which are the major storage sites for renin.
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