'Lose the plot' means to go crazy.

“Lose the plot”的意思是发疯。

For example, you could say: 'Steve has absolutely lost the plot.

例如，你可以说：“史蒂夫完全疯了。

That's like you've, you've kind of gone off, like I really lost the plot.

比如说你离开一会错过了一些情节。

His main point was that Unilever had lost the plot, he said, by focusing on sustainability.

他的主要观点是，联合利华已经迷失了方向，因为过于专注于可持续发展。

He said that any company that feels it has to define the purpose of Hellmann's mayonnaise has lost the plot.

他说，任何公司如果觉得自己必须定义 Hellmann 蛋黄酱的目的，那就已经失去了意义。

And she was like, oh, he is lost the plot.

她就像，哦，他失去了情节。

I could see people thinking I’d totally lost the plot.

【lose】我看得出来，人们都以为我彻底疯了。