| 单词 | Loading dose |
| 释义 |
Loading dose
原声例句
医学之光：人类与疾病的斗争 Given the changing clinical presentation and concern about hospital-acquired pneumonia, treatment with vancomycin (a 1750-mg loading dose followed by 1 g administered intravenously every 8 hours) and cefepime (administered intravenously every 8 hours) was initiated. 鉴于不断变化的临床表现和对医院获得性肺炎的担忧， 开始使用万古霉素（1750 mg 负荷剂量， 随后每 8 小时静脉注射 1 g）和头孢吡肟（每 8 小时静脉注射）进行治疗。
英语百科
Loading doseA loading dose is an initial higher dose of a drug that may be given at the beginning of a course of treatment before dropping down to a lower maintenance dose. A loading dose is most useful for drugs that are eliminated from the body relatively slowly, i.e. have a long systemic half-life. Such drugs need only a low maintenance dose in order to keep the amount of the drug in the body at the appropriate therapeutic level, but this also means that, without an initial higher dose, it would take a long time for the amount of the drug in the body to reach that level. |
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