托法娜仙液（Aqua Tofana），17世纪意大利北部流行的一种美白化妆水，含有亚砷酸成分，据说为南意大利名为脱芬妮雅（Tofana）的老太太利用火山析出的矿物调配而成。由于慢性砷中毒在当时的医疗水准下难以与一般慢性病分别，故当时许多慢性毒杀亲夫的案件都是以这种化妆水犯案。事后遭到政府禁止贩卖。

Aqua Tofana (also known as Acqua Toffana, Aqua Tophana, and Aqua Tufania and "Manna di San Nicola") was a strong poison that was reputedly widely used in Naples and Rome, Italy. During the early 17th century Giulia Tofana, or Tofania, an infamous lady from Palermo, made a good business for over fifty years selling her large production (she employed her daughter and several other lady helpers) of Aqua Tofana to would-be widows.