Leucyl aminopeptidase

Shown are the LAP-A residues in the active site. Two Zn+2 cations are also shown, along with a water and a bicarbonate ion that acts as a general base.

In this mechanism, the bicarbonate ion acts as a general base. For LAP-A, R1 could be the R group of leucine, methionine, or arginine.

Shown above is the pathway as studied in tomato.

Leucyl aminopeptidases (EC3.4.11.1, leucine aminopeptidase, LAPs, leucyl peptidase, peptidase S, cytosol aminopeptidase, cathepsin III, L-leucine aminopeptidase, leucinaminopeptidase, leucinamide aminopeptidase, FTBL proteins, proteinates FTBL, aminopeptidase II, aminopeptidase III, aminopeptidase I) are enzymes that preferentially catalyze the hydrolysis of leucine residues at the N-terminus of peptides and proteins. Other N-terminal residues can also be cleaved, however. LAPs have been found across superkingdoms. Identified LAPs include human LAP, bovine lens LAP, porcine LAP, Escherichia coli (E. coli) LAP (also known as PepA or XerB), and the solanaceous-specific acidic LAP (LAP-A) in tomato (Solanum lycopersicum).

单词	Leucyl aminopeptidase
释义	Leucyl aminopeptidase 英语百科 Leucyl aminopeptidase Leucyl aminopeptidases (EC3.4.11.1, leucine aminopeptidase, LAPs, leucyl peptidase, peptidase S, cytosol aminopeptidase, cathepsin III, L-leucine aminopeptidase, leucinaminopeptidase, leucinamide aminopeptidase, FTBL proteins, proteinates FTBL, aminopeptidase II, aminopeptidase III, aminopeptidase I) are enzymes that preferentially catalyze the hydrolysis of leucine residues at the N-terminus of peptides and proteins. Other N-terminal residues can also be cleaved, however. LAPs have been found across superkingdoms. Identified LAPs include human LAP, bovine lens LAP, porcine LAP, Escherichia coli (E. coli) LAP (also known as PepA or XerB), and the solanaceous-specific acidic LAP (LAP-A) in tomato (Solanum lycopersicum).
随便看	cutis vera的意思 cutis vera tuberculosis的意思 cutis verrucosa tuberculosis的意思 Cutis verticis gyrata的意思 cutis verticis gyrata and mental retardation syndrome的意思 Cut It的意思 cut it close的意思 cut it fat的意思 cut it fine的意思 cutitis的意思 Cut It Out的意思 cut it out!的意思 cut it rather fine的意思 cut it short的意思 cut it too fat的意思 cutituberculin reaction的意思 cut it up的意思 Cutivate的意思 Cutivated Purple Perilla Perennial Calyx的意思 Cutivated Purple Perilla Root的意思 Cutivated Purple Perilla Stem的意思 cutivitol的意思 cutization的意思 cutizon的意思 cutizone的意思