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单词 Leuckart reaction
释义

Leuckart reaction

中文百科

刘卡特反应

The mechanism depicts the conversion of ketone (or aldehyde) to an amine using ammonium formate as a reagent.
The scheme depicts the mechanism for the Leuckart reaction using formamide as the reducing agent.
Hydrolysis of imine

刘卡特反应是甲酸的铵盐与醛(或酮)通过还原胺化形成胺的化学反应。该反应以鲁道夫·刘卡特命名。

除了氨以外,伯胺和仲胺也是成功的。

当使用过量甲酸时,该反应称为刘卡特-瓦拉赫反应,以鲁道夫·刘卡特和奥托·瓦拉赫命名。

英语百科

Leuckart reaction 刘卡特反应

The ketone is converted to an amine via reductive amination using ammonium formate
The mechanism depicts the conversion of ketone (or aldehyde) to an amine using ammonium formate as a reagent.
The scheme depicts the mechanism for the Leuckart reaction using formamide as the reducing agent.
Hydrolysis of imine

The Leuckart reaction is the chemical reaction that converts aldehydes or ketones to amines by reductive amination in the presence of heat. The reaction, named after Rudolf Leuckart, proceeds via two mechanisms: one using ammonium formate and the other using formamide as the reducing agent. It requires high temperatures, usually between 120 and 130 °C, although under the presence of formamide, the temperature can be greater than 165 °C. The reaction works best using ammonium formate and the general reaction can be seen below.

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更新时间:2025/6/18 1:59:11