Lethal white syndrome

The two horses on the right exhibit the frame overo pattern.

This horse has irregular white markings, and would be classed by the APHA and PtHA as

This Thoroughbred mare was born pure white with pink skin. Such foals are occasionally born with no apparent white ancestry. This mare does not carry the LWS gene, and her coat is termed

This blue-eyed, pink-skinned, whitish filly is in fact a cremello, and is perfectly healthy. Her skin is a rosier shade and her coat cream-colored, as opposed to stark white.

Lethal white syndrome (LWS), also called overo lethal white syndrome (OLWS), lethal white overo (LWO), and overo lethal white foal syndrome (OLWFS), is an autosomal genetic disorder most prevalent in the American Paint Horse. Affected foals are born after the full 11-month gestation and externally appear normal, though they have all-white or nearly all-white coats and blue eyes. However, internally, these foals have a nonfunctioning colon. Within a few hours, signs of colic appear; affected foals die within a few days. Because the death is often painful, such foals often are humanely euthanized once identified. The disease is particularly devastating because foals are born seemingly healthy after being carried to full term.

单词	Lethal white syndrome
释义	Lethal white syndrome 英语百科 Lethal white syndrome Lethal white syndrome (LWS), also called overo lethal white syndrome (OLWS), lethal white overo (LWO), and overo lethal white foal syndrome (OLWFS), is an autosomal genetic disorder most prevalent in the American Paint Horse. Affected foals are born after the full 11-month gestation and externally appear normal, though they have all-white or nearly all-white coats and blue eyes. However, internally, these foals have a nonfunctioning colon. Within a few hours, signs of colic appear; affected foals die within a few days. Because the death is often painful, such foals often are humanely euthanized once identified. The disease is particularly devastating because foals are born seemingly healthy after being carried to full term.
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