In really large doses, acrylamide totally is toxic.

在非常大的剂量下，丙烯酰胺是有毒的。

" Wolf Larsen, in large doses, " I murmured, " before and after taking" .

" 吃一服叫海狼拉尔森的药，大剂量的，" 我喃喃地说，" 前后对比。"

Greedily she clamoured for ever larger, ever more frequent doses.

她不断贪婪地吵着要求增加唆麻的剂量和次数。

The more you use, the larger dose you may need to get the same relief.

你使用的次数越多，你可能需要更多的剂量才能得到同样的缓解。

So, the more you use, the larger dose you need to get the same effect.

因此，你所使用的剂量越多，获得同样效果所需的剂量就越大。

At large doses, ibuprofen can cause serious adverse effects and may even be fatal.

大剂量布洛芬可引起严重的不良反应，甚至可能致命。

Drugs that are safe in the dosage stated on the label may be very dangerous in large doses.

服用标签上的剂量很安全，但大量服用就可能很危险。

They can develop tolerance and require increasingly large doses over time.

随着时间的推移，他们会产生耐受性并需要越来越大的剂量。

Small doses can give you hallucinogenic effects, larger doses would be fatal.

小剂量会给你带来致幻作用，大剂量会致命。

Larger doses will thin your blood and cause you to bleed internally.

更大的剂量会稀释你的血液并导致你内出血。

Stimulants can aggravate anxiety and—in large doses—even trigger panic attacks.

兴奋剂会加重焦虑， 大剂量时甚至会引发惊恐发作。

I went home and took a large dose of bicarbonate of soda.

我回家后服用了大剂量的碳酸氢钠。

Well, for one, our body can build up a tolerance. So, the more you use, the larger dose you need to get the same effect.

首先，我们身体的耐受性会增加。这样一来，你服用的药物越多，你要达到同样效果所需的剂量就越大。

This is a risk for people taking warfarin, especially in large doses, without an overlapping rapid-onset blood thinner such as heparin or low molecular weight heparin.

这在服用华法林的患者中存在风险，尤其是当大剂量使用且没有叠加使用如肝素或低分子量肝素等速效血液稀释剂时。

But for this to work, it also requires a much larger dose than people would typically get from drinking a few cups of coffee in a day.

但要让它起作用，它需要的剂量也比人们通常每天喝几杯咖啡所获得的剂量大得多。

To experience the same release of dopamine and resulting mood effects as before, people have to take larger and larger doses— a cycle that leads to physical dependence and addiction.

要想体验与以往等同的多巴胺分泌和相应的情绪作用，人们就必须服用越来越大的剂量，而这一循环会导致身体产生药物依赖性和成瘾。

In addition to potentially causing a severe allergic reaction in certain individuals, large doses of their venom can result in cardiac arrest or organ failure.

除了可能对某些人造成严重的过敏反应外，大剂量的毒液还会导致心脏骤停或器官衰竭。

This increased availability of calcium increases the power output of the muscles, but it does require a pretty large dose to occur, around 500 mg for an average person.

这增加了钙的可用性，增加了肌肉的能量输出，但它确实需要一个相当大的剂量，大约500毫克。

It’s quite unbelievable what they would try and make test subjects do, after say a large dose of drugs or days of brainwashing tied to a chair.

在服用大剂量药物或绑在椅子上洗脑几天之后，他们会尝试让测试对象做什么，这真是令人难以置信。

At approximately 11pm on the night of the 20th of January 1936 he effectively decided to speed along the king's death, administering a large dose of morphine and cocaine sometime afterwards.

1936 年 1 月 20 日晚上 11 点左右， 他实际上决定加速国王的死亡，随后服用了大剂量的吗啡和可卡因。