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单词 Lactose operon
释义

Lactose operon

英语百科

lac operon

The lac operon. Top:Repressed, Bottom:Active. 
1: RNA Polymerase, 2: Repressor, 3: Promoter, 4: Operator, 5: Lactose, 6: lacZ, 7: lacY, 8: lacA.
Structure of lactose and the products of its cleavage.
Tetrameric LacI binds two operator sequences and induces DNA looping.  Two dimeric LacI functional subunits (red+blue and green+orange) each bind a DNA operator sequence (labeled).  These two functional subunits are coupled at the tetramerization region (labeled); thus, tetrameric LacI binds two operator sequences.  This allows tetrameric LacI to induce DNA looping.
IPTG

lac operon (lactose operon) is an operon required for the transport and metabolism of lactose in Escherichia coli and many other enteric bacteria. Although glucose is the preferred carbon source for most bacteria, the lac operon allows for the effective digestion of lactose when glucose is not available. Gene regulation of the lac operon was the first genetic regulatory mechanism to be understood clearly, so it has become a foremost example of prokaryotic gene regulation. It is often discussed in introductory molecular and cellular biology classes at universities for this reason.

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更新时间:2025/6/22 3:31:32