柯达克罗姆（Kodachrome）是一款彩色幻灯片品牌，由美国伊士曼柯达公司（Eastman Kodak）拥有。柯达克罗姆是世界上第一款成功大量销售的使用减色法三层乳剂的彩色幻灯片，也是第一款真正意义上的多层彩色胶片。发明者为柯达公司的小利奥波德·戈多夫斯基（Leopold Godowsky, Jr.）和利奥波德·曼内斯（Leopold Mannes）。此幻灯片需以K-14冲印处理冲印。

柯达克罗姆从1935年开始上市一直到生产到2009年，也是世界上使用时间最长的一款彩色幻灯片。2010年12月30日，全球最后一家可冲印柯达克罗姆幻灯片的美国堪萨斯州Dwayne's Photo公司终止该幻灯片的冲印服务。

Kodachrome is a brand name for a non-substantive, color reversal film introduced by Eastman Kodak in 1935. It was one of the first successful color materials and was used for both cinematography and still photography. Because of its complex processing requirements, the film was sold process-paid in the United States until 1954 when a legal ruling prohibited this. Elsewhere, this arrangement continued. For many years it was used for professional color photography, especially for images intended for publication in print media. Because of the growth and popularity of alternative photographic materials, its complex processing requirements, and the widespread transition to digital photography, Kodachrome lost its market share, its manufacturing was discontinued in 2009 and its processing ended in December 2010.