凯瑟琳·霍顿·赫本（英语：Katharine Houghton Hepburn，1907年5月12日－2003年6月29日），生于美国康涅狄格州，美国国宝级电影女演员，美国电影与戏剧界的标志性人物、好莱坞的传奇。凯瑟琳·赫本近六十年的演艺生涯横跨数种表演类型，有“美国影坛第一夫人”美誉，她亦是美国奥斯卡金像奖自1929年创立以来，唯一一位能四度摘下奥斯卡影后的女星。1999年，美国电影学会将凯瑟琳·赫本评为美国影视史上最伟大的女演员。

Katharine Houghton Hepburn (May 12, 1907 – June 29, 2003) was an American actress. Known for her fierce independence and spirited personality, Hepburn was a leading lady in Hollywood for more than 60 years. She appeared in a range of genres, from screwball comedy to literary drama, and she received four Academy Awards for Best Actress—a record for any performer. In 1999, Hepburn was named by the American Film Institute as the greatest female star of Classic Hollywood Cinema.