卡尔派尼西（希腊语：Καρπενήσι）一作卡尔派尼西翁，为希腊中部中希腊大区城市，埃夫里塔尼亚州首府。地处河谷地带，周围群山环绕，为希腊著名的滑雪胜地。

Karpenisi (Greek:Καρπενήσι) is a town in central Greece. It is the capital of the regional unit of Evrytania. Karpenisi is situated in the valley of the river Karpenisiotis (Καρπενησιώτης), a tributary of the Megdovas, in the southern part of the Pindus Mountains. Mount Tymfristos (2,315 m elevation) lies directly to the north of the town, and the foothills of mount Kaliakouda are in the south. Karpenisi has a ski resort and is a popular destination, especially during winter. It is called Switzerland of Greece for the resemblance with the mountainous country and its beauty, atypical for a Mediterranean place.