宇智波鼬（うちはイタチ，Uchiha Itachi）是日本动漫系列《火影忍者》中的角色。

宇智波佐助的兄长，特征是黑色长发，从近鼻翼的眼角延伸至眼下的深邃纹路，代表「朱雀」的「朱」字戒指，佩戴在右手无名指上，脖子戴有项链。为人沉着冷静，天赋极佳的他，七岁以第一名的成绩从忍者学校毕业（六岁入学），八岁时因带土杀光他的同伴即能使用写轮眼，十岁升为中忍，被称为「天才忍者」，十三岁就担任木叶忍者村的暗部分队长，是家族的骄傲。但在一个晚上却突然将宇智波一族几乎全灭后，离开木叶成为叛忍，并加入组织「晓」(实则为了保护木叶忍者村而加入晓当间谍)。他的弟弟宇智波佐助成为宇智波家族中唯一的活口，自始不惜一切以杀死他为目标，为族人复仇。

Itachi Uchiha(うちは イタチ,Uchiha Itachi) is a fictional character in the Naruto manga and anime series created by Masashi Kishimoto. Itachi is the older brother of Sasuke Uchiha and is responsible for killing all the members of their clan, sparing only Sasuke. Though treated as an antagonist for much of the series, it is later revealed that Itachi slaughtered his clan in order to prevent a coup d'état which would result in a war, and that he had been acting in both Konoha's and Sasuke's best interests for the entire series.