The Isthmus of Tehuantepec (Spanish pronunciation: [tewanteˈpek]) is an isthmus in Mexico. It represents the shortest distance between the Gulf of Mexico and the Pacific Ocean. Prior to the opening of the Panama Canal, it was a major shipping route known simply as the Tehuantepec Route. The name is taken from the town of Santo Domingo Tehuantepec in the state of Oaxaca; this was derived from the Nahuatl term tecuani-tepec ("jaguar hill").