In females, primary sex characteristic dysfunction includes amenorrhea or absence of menstruation, or oligomenorrhea or irregular menstrual cycle.

在女性中，第一性征的功能障碍包括闭经，即无月经，或月经减少，即月经周期不规则。

We didn't have any data about irregular menstrual cycles from clinical trials to point to, and that is problematic.

我们没有任何关于月经周期不规律的临床试验数据，这是有问题的。