Low levels of ionized calcium affect a variety of cellular processes, in particular, electrically active neurons.

低水平的离子钙会影响多种细胞过程，特别是神经元的电活动。

This might happen when too much ionized calcium is excreted.

当过多的钙离子被排出体外时，可能会发生这种情况。

The phosphate binds to the ionized calcium and forms calcium phosphate, making it insoluble and effectively decreasing the total amount in blood.

磷与钙离子结合形成磷酸钙，使其不溶于水，并大大减少血液中的总钙量。

This is therefore called false hypocalcemia or pseudohypocalcemia, since there's less overall calcium due to less bound calcium, but the free ionized calcium levels are still the same.

这就被称作假性低钙血症，因为总钙减少是因为结合钙减少，但游离钙水平仍然不变。

Because most of phosphate is locked up with calcium in the bones, the levels of phosphate are heavily tied with the levels of ionized calcium in the body.

因为大部分磷酸盐和骨骼中的钙结合在一起，磷酸盐的含量与体内游离钙的含量密切相关。

Now, because most of phosphate is locked up with calcium in the bones, the levels of phosphate are heavily tied with the levels of ionized calcium in the body.

因为大部分的磷酸盐和骨骼中的钙结合在一起，磷酸盐的水平与体内的钙离子水平密切相关。

Other inflammatory processes can also be a cause, like acute pancreatitis because free fatty acids end up binding to ionized calcium, which is also insoluble and precipitates out as a soap-like substance.

其它炎症过程也可能引发低钙血症，例如急性胰腺炎，因为游离脂肪酸最终与离子钙结合，形成不溶于水的物质，并以类似肥皂状物质的形式沉淀。

So when the dust settles, as a result of parathyroid hormone, phosphate is lost in the urine while ionized calcium is kept in the blood, so ionized calcium levels rise and phosphate levels fall!

所以最终导致的结果是磷酸盐在尿液中丢失，而游离钙被保存在血液中，因此游离钙含量上升，而磷酸盐含量下降！

Also, any condition that results in hypoalbuminemia or low albumin levels, would lead to a loss of bound calcium, while at the same time free ionized calcium concentrations stay essentially the same due to hormonal regulation.

此外，任何可能导致低白蛋白血症，即白蛋白水平低下的情况，也会导致结合钙的减少；同时，游离钙的浓度因为激素的调控基本保持不变。

Alright, as a quick recap, hypocalcemia describes a low concentration of free ionized calcium in the blood, which most commonly results from defective production of calcium controlling hormones, like parathyroid hormone and active vitamin D.

得！快速回顾一下：低钙血症意味着血液中游离离子钙的浓度低，最常见的原因是钙调控激素如甲状旁腺激素和活性维生素D的生成出现问题。

As soon as the positively-charged calcium and negatively-charged phosphate are released from the bones, they grab onto each other again, meaning that the ionized calcium level doesn't really go up very much at all.

一旦带正电的钙和带负电的磷酸盐从骨头中被释放出来，它们又再次相互吸附，这意味着游离钙离子的水平并没有上升很多。

Because the total serum calcium includes albumin bound and free ionized calcium, of which only the latter is physiologically active.

因为血清总钙包括白蛋白结合钙和游离钙，其中只有游离钙具有生理活性。

And so even though the total levels of calcium are the same, there's less ionized calcium which is the one that's important for cellular processes and can lead to symptoms of hypocalcemia.

因此，即使钙的总含量相同，游离钙减少了，它对细胞过程很重要，会产生低钙血症的症状。

On the other hand, in conditions with high blood pH, albumin binds more calcium leaving less free ionized calcium in the serum, while the total calcium level may appear normal.

另一方面，在血液pH较高情况下，白蛋白结合更多的钙，从而使血清中的游离钙减少，而总钙水平可能看起来正常。