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单词 Ionic channels
释义

Ionic channels

中文百科

离子信道 Ion channel

(重定向自Ionic channels)
离子信道示意图。1 - 信道蛋白质结构(通常每个信道有四个同源亚基[1]), 2 - 外前庭, 3 - 选择性过滤器*, 4 - 选择性过滤器的直径, 5 - 磷酸化位点, 6 - 细胞膜.
Birth of an Idea (2007) 朱利安·沃斯-安德烈受罗德里克·麦金农委托制作的一个雕像,该雕像是基于麦金农团队于2001年发现的分子三维结构创作的。

离子信道(英语:Ion channel)是一种成孔蛋白,它通过允许某种特定类型的离子依靠电化学梯度穿过该信道,来帮助细胞创建和控制质膜间的微弱电压压差(参见细胞电势)。这些离子信道存在于所有细胞的细胞膜上。针对离子信道的研究叫做信道学,这一研究涉及了许多许多科学技术,例如电流生理学的电压钳位(尤其是膜片钳位技术)、免疫组织化学以及逆转录。

英语百科

Ion channel 离子通道

(重定向自Ionic channels)
Schematic diagram of an ion channel. 1 - channel domains (typically four per channel), 2 - outer vestibule, 3 - selectivity filter, 4 - diameter of selectivity filter, 5 - phosphorylation site, 6 - cell membrane.
Birth of an Idea (2007) by Julian Voss-Andreae. The sculpture was commissioned by Roderick MacKinnon based on the molecule's atomic coordinates that were determined by MacKinnon's group in 2001.
Not to be confused with: Ion Television or Ion implantation.

Ion channels are pore-forming membrane proteins whose functions include establishing a resting membrane potential, shaping action potentials and other electrical signals by gating the flow of ions across the cell membrane, controlling the flow of ions across secretory and epithelial cells, and regulating cell volume. Ion channels are present in the membranes of all cells. Ion channels are considered to be one of the two traditional classes of ionophoric proteins, with the other class known as ion transporters (including the sodium-potassium pump, sodium-calcium exchanger, and sodium-glucose transport proteins, amongst others).

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更新时间:2025/6/19 2:54:25