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单词 Internexin
释义

Internexin

英语百科

Internexin

Mixed neuron/glial cultures from p18 rat embryo brain stained with antibody to alpha-internexin which reveals, in red, neuronal processes and cell bodies. Cells were also labelled in green for Coronin 1a, a marker for microglia.

Internexin, alpha-internexin, is a Class IV intermediate filament approximately 66 KDa. The protein was originally purified from rat optic nerve and spinal cord. The protein copurifies with other neurofilament subunits, as it was originally discovered, however in some mature neurons it can be the only neurofilament expressed. The protein is present in developing neuroblasts and in the Central Nervous System of adults. The protein is a major component of the intermediate filament network in small interneurons and cerebellar granule cells, where it is present in the parallel fibers.

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更新时间:2025/6/18 5:57:03