VLA-4

（重定向自Integrin alpha4beta1）

Integrin alpha4beta1 (Very Late Antigen-4) is an integrin dimer. It is composed of CD49d (alpha 4) and CD29 (beta 1).

Vascular cell adhesion molecule-1 (VCAM-1 - an integrin receptor) located on an endothelial cell, binds to the integrin VLA-4 which are normally expressed on leukocyte plasma membranes, but they do not adhere to their appropriate ligands until the leukocytes are activated by chemotactic agents or other stimuli (often produced by the endothelium or other cells at the site of injury). Only then do the integrins undergo the conformational change necessary to confer high binding affinity for the endothelial adhesion molecules.

单词	Integrin alpha4beta1
释义	Integrin alpha4beta1 英语百科 VLA-4 （重定向自Integrin alpha4beta1） Integrin alpha4beta1 (Very Late Antigen-4) is an integrin dimer. It is composed of CD49d (alpha 4) and CD29 (beta 1). Vascular cell adhesion molecule-1 (VCAM-1 - an integrin receptor) located on an endothelial cell, binds to the integrin VLA-4 which are normally expressed on leukocyte plasma membranes, but they do not adhere to their appropriate ligands until the leukocytes are activated by chemotactic agents or other stimuli (often produced by the endothelium or other cells at the site of injury). Only then do the integrins undergo the conformational change necessary to confer high binding affinity for the endothelial adhesion molecules.
随便看	continuous zone refiner的意思 continuous zone refining的意思 continuous zone refining apparatus的意思 Continu process的意思 continute的意思 continuua的意思 continuum的意思 continuum absorption的意思 continuum approximation的意思 continuum boundary的意思 continuum burst的意思 continuum concept of vegetation的意思 continuum, continuous medium的意思 continuum damage mechanics的意思 continuum effect的意思 continuum emission的意思 continuum flow的意思 continuum fringe visibility的意思 Continuum hypothesis的意思 continuum index的意思 continuum lamp的意思 continuum light source的意思 continuumlike的意思 continuum mechanic的意思 Continuum mechanics的意思