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单词 Integral monotopic protein
释义

Integral monotopic protein

英语百科

Integral monotopic protein

Schematic representation of the different types of interaction between monotopic membrane proteins and the cell membrane:
1. interaction by an amphipathic α-helix parallel to the membrane plane (in-plane membrane helix)
2. interaction by a hydrophobic loop
3. interaction by a covalently bound membrane lipid (lipidation)
4. electrostatic or ionic interactions with membrane lipids (e.g. through a calcium ion)

Integral monotopic proteins, are permanently attached to the membrane from one side.

Three-dimensional structures of the following integral monotopic proteins have been determined:

There are also structures of integral monotopic domains of transmembrane proteins:

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更新时间:2025/6/20 1:02:30