Inositol trisphosphate

IP3 anion with oxygen atoms(red) and the hydrogen atoms(dark blue) involved in docking to the InsP3R labelled

PLC cleavage of PIP2 to IP3 and DAG initiates intracellular calcium release and PKC activation.

Inositol trisphosphate or inositol 1,4,5-trisphosphate (also commonly known as triphosphoinositol; abbreviated InsP₃ or Ins3P or IP₃), together with diacylglycerol (DAG), is a secondary messenger molecule used in signal transduction and lipid signaling in biological cells. While DAG stays inside the membrane, IP₃ is soluble and diffuses through the cell. It is made by hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP₂), a phospholipid that is located in the plasma membrane, by phospholipase C (PLC).

单词	Inositol triphosphate
释义	Inositol triphosphate 英语百科 Inositol trisphosphate Inositol trisphosphate or inositol 1,4,5-trisphosphate (also commonly known as triphosphoinositol; abbreviated InsP₃ or Ins3P or IP₃), together with diacylglycerol (DAG), is a secondary messenger molecule used in signal transduction and lipid signaling in biological cells. While DAG stays inside the membrane, IP₃ is soluble and diffuses through the cell. It is made by hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP₂), a phospholipid that is located in the plasma membrane, by phospholipase C (PLC).
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Inositol triphosphate

Inositol trisphosphate