In extreme cases, they can even cause skin cancer.

在极端条件下，甚至还会导致皮肤癌。

Sometimes 15 to 20 degrees hotter in extreme cases.

有时候遇到一些极端情况，甚至会高出15到20摄氏度。

In extreme cases, this can cause pits in the teeth.

在极端情况下，这可能导致牙齿上出现坑洞。

And while rare, in extreme cases, too much caffeine can kill you.

虽然很少见，但在极端的情况下，摄入过量咖啡因能够导致死亡。

But at least protection from the elements in extreme cases of weather.

但至少能在极端天气情况下抵御恶劣的天气。

In extreme cases, the food particles can cause infection or even death.

在极端情况下，食物颗粒可能会导致感染甚至死亡。

In extreme cases, diabetics may decrease, delay or even stop taking their insulin.

在极端情况下，糖尿病患者可能减少、延迟甚至停止服用胰岛素。

Symptoms include nausea, vomiting, diarrhea, nerve damage and even death in extreme cases.

症状包括恶心、呕吐、腹泻、神经损害而且极端情况下甚至致死。

In extreme cases, believe it or not, people have died from overdosing on caffeine.

在一些极端例子中 无论你信不信 有的人因过度摄入咖啡因而丧命。

This can cause enormous amounts of pain, paralysis, and even death in extreme cases.

在极端情况下，这会导致巨大的疼痛、瘫痪甚至死亡。

In extreme cases, parents can be sentenced to jail if their children are absent from school too often.

在极端情况下，如果孩子经常缺课，父母可能会被判入狱。

In extreme cases, electroconvulsive therapy, which is like a controlled seizure in the patient's brain, is also very helpful.

在一些特殊的病例中，甚至电休克疗法，即一种像是控制病患大脑进行休克的方法，也有一定疗效。

In extreme cases, like what might happen to the Maldives in a few decades, entire landmasses may become completely swallowed.

在极端情况下，比如马尔代夫在几十年后可能会发生怎样的情况，整个大陆可能会被完全吞没。

In extreme cases, schizophrenia can result in catatonia, which is the inability to move or respond, although that's super rare.

在极端的情况下，精神分裂症会导致紧张症，即不能运动或反应，尽管这种情况非常罕见。

Each has inadvertently created a drug interaction that could, in extreme cases, lead to kidney failure; liver damage; or internal bleeding.

每个人都在无意中创造了一种药物相互作用——在极端情况下，可能导致肾衰竭、肝损伤，或内出血。

Early bathing advocates even warned against its use except in extreme cases.

早期沐浴倡导者甚至警告不要使用它，除非在极端情况下。

In extreme cases, some people have surgery to tighten the LES to minimize their distress.

在极端情况下，有些人会通过手术收紧 LES 以尽量减少他们的痛苦。

In extreme cases it can even lead to suicide, though this is thankfully rare.

在极端情 况下甚至有可能导致自杀，尽管这种情况尚不多见。

But in extreme cases like severe heat exhaustion or heat stroke, immediate medical attention is crucial.

但在严重热衰竭或中暑等极端情况下，立即就医至关重要。

In extreme cases, a woman needing only antibiotics to clear up a minor infection, might have her entire uterus removed in a surgical procedure.

在极端情况下，只需要抗生素来清除轻微感染的妇女可能会在外科手术中切除整个子宫。