IMP dehydrogenase

IMP dehydrogenase EC1.1.1.205 (Inosine-5'-monophosphate dehydrogenase) (Inosinic acid dehydrogenaseis) (IMPDH) an enzyme that converts inosine monophosphate to xanthosine monophosphate:
It catalyzes the rate-limiting reaction of de novo GTP biosynthesis.