Immunogold labelling

Two images produced using immunogold labeling and transmission electron microscopy: (A) Gold particles are marking mtDNA near the mitochondria (B) mtDNA marked with gold particles after extraction.[1]

Immunogold labeling or Immunogold staining (IGS) is a staining technique used in electron microscopy. This staining technique follow the same patterns of the Indirect immunofluorescence : colloidal gold particles are most often attached to secondary antibodies which are in turn attached to primary antibodies designed to bind a specific antigen or other cell component. Gold is used for its high electron density which increases electron scatter to give high contrast 'dark spots'.

单词	Immunogold staining
释义	Immunogold staining 英语百科 Immunogold labelling Immunogold labeling or Immunogold staining (IGS) is a staining technique used in electron microscopy. This staining technique follow the same patterns of the Indirect immunofluorescence : colloidal gold particles are most often attached to secondary antibodies which are in turn attached to primary antibodies designed to bind a specific antigen or other cell component. Gold is used for its high electron density which increases electron scatter to give high contrast 'dark spots'.
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