Insulin lispro

（重定向自Humalog）

Insulin lispro (marketed by Eli Lilly and Company as "Humalog") is a fast acting insulin analog. It was first approved for use in the United States in 1996, making it the first insulin analog to enter the market.

Engineered through recombinant DNA technology, the penultimate lysine and proline residues on the C-terminal end of the B-chain are reversed. This modification does not alter receptor binding, but blocks the formation of insulin dimers and hexamers. This allowed larger amounts of active monomeric insulin to be immediately available for postprandial injections.

单词	Humalog
释义	Humalog 英语百科 Insulin lispro （重定向自Humalog） Insulin lispro (marketed by Eli Lilly and Company as "Humalog") is a fast acting insulin analog. It was first approved for use in the United States in 1996, making it the first insulin analog to enter the market. Engineered through recombinant DNA technology, the penultimate lysine and proline residues on the C-terminal end of the B-chain are reversed. This modification does not alter receptor binding, but blocks the formation of insulin dimers and hexamers. This allowed larger amounts of active monomeric insulin to be immediately available for postprandial injections.
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