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单词 HPRT
释义

HPRT

中文百科

次黄嘌呤-鸟嘌呤磷酸核苷转移酶 Hypoxanthine-guanine phosphoribosyltransferase

(重定向自HPRT)

次黄嘌呤-鸟嘌呤磷酸核苷转移酶(Hypoxanthine-guanine phosphoribosyltransferase,简称HGPRT)为人体内一个转译自HPRT1基因的酵素

HGPRT为一种转移酶,可以催化将次黄嘌呤转换为肌苷酸(IMP),也可将鸟嘌呤的反应转为单磷酸鸟苷。这两个反应都是将PRPP的5-磷酸核苷转移至嘌呤上。HGPRT在核苷酸再利用合成途径中扮演重要角色。

英语百科

Hypoxanthine-guanine phosphoribosyltransferase 次黄嘌呤-鸟嘌呤磷酸核苷转移酶

(重定向自HPRT)

Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) is an enzyme encoded in humans by the HPRT1 gene.

HGPRT is a transferase that catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate. This reaction transfers the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate (PRPP) to the purine. HGPRT plays a central role in the generation of purine nucleotides through the purine salvage pathway.

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更新时间:2025/6/18 18:59:17