无防兽（学名Anoplotherium）是一属已灭绝的有蹄类。牠们生存于始新世晚期至渐新世早期。牠们的化石最初是于法国巴黎发现。

Anoplotherium is an extinct genus of ungulates which lived from the Late Eocene to the earliest Oligocene. It was first found in the gypsum quarries near Paris.

This animal probably weighed about 80 kg, a weight comparable to that of the living llama.