Also, any condition that results in hypoalbuminemia or low albumin levels, would lead to a loss of bound calcium, while at the same time free ionized calcium concentrations stay essentially the same due to hormonal regulation.

此外，任何可能导致低白蛋白血症，即白蛋白水平低下的情况，也会导致结合钙的减少；同时，游离钙的浓度因为激素的调控基本保持不变。