人亚科（Homininae）是人科下的亚科，当中包括了人类及其已灭绝的亲属，以及大猩猩及黑猩猩。它亦包含了所有的原始人类，如南方古猿。

直至1980年前，人科都只得人类一个种，而其他的都是属于猩猩科。但不同的发现逼使重新检讨这个分类，人科之下再分为猩猩亚科及人亚科。后来却发现大猩猩及黑猩猩较接近人类，故牠们亦被包含在人亚科中。人猿总科的分类亦不断的有所改变。

人亚科可以再细分为大猩猩族及人族，大猩猩族就只有大猩猩，而人族则包含人类及黑猩猩。中新世晚期的纳卡里猿仲山种与同期的欧兰猿可能就是这个分支的基底成员，并不属于其下的两个族。人亚科估计在800万年前才开始分开演化。

Homininae is a subfamily of Hominidae that includes the tribes Hominini and Gorillini, which together encompass humans and some extinct relatives, chimpanzees and bonobos, as well as gorillas. It comprises all hominids that arose after orangutans (subfamily Ponginae) split from the line of great apes. The Homininae cladogram has three main branches, which lead to gorillas (through the tribe Gorillini), and to humans and chimpanzees via the tribe Hominini and subtribes Hominina and Panina, (see the evolutionary tree below). There are two living species of chimpanzees and two living species of gorillas, but only one extant human species. Traces of hypothetical Homo species, including Homo floresiensis and Homo denisova, have been found with dates as recent as 12,000 years ago. Organisms in this class are described as hominine or hominines (not to be confused with the terms hominins or hominini).