In principle, the decision is highly significant.

原则上，这个决定意义重大。

Revealing one's sexuality, especially for the first time, is still a highly significant moment.

暴露自己的性取向，尤其是第一次，仍然是一个非常重要的时刻。

On days randomized to coffee, people took on average about 1000 more steps, which is highly significant.

在随机喝咖啡的日子里，人们平均多走了大约 1000 步，这非常有意义。

Tuesday is a highly significant day for the nation of North Korea.

AZUZ：周二对朝鲜民族来说是一个非常重要的日子。

The result is highly significant for the future of the province.

【significant】这一结果对该省的未来极为重要。

How then are these highly significant daily, even hourly, revaluations of existing investments carried out in practice?

那么，这些每天甚至每小时对现有投资进行的非常重要的重估在实践中是如何进行的呢？

He wasn't sorry that there were no Dementors nearby, but now he came to think of it, their absence was highly significant.

他并不为附近没有摄魂怪而遗憾。但想起来这个现象的确耐人寻味。

In reality, the pacific ocean takes up approximately one-third of the planet's surface which is still a highly significant amount, significant enough to produce a map like this one.

事实上，太平洋约占地球表面的三分之一，这仍然是非常可观的面积，大到足以制作出这样一幅地图。

In 2010, the World Health Organization estimated that 1 billion people on the planet live with some form of disability, with over 110 million having highly significant difficulties in functioning.

2010 年，世界卫生组织估算世界上大约有 10 亿人存在某种形式的残疾，有超过 1.1 亿人的身体机能存在严重问题。

While the war with Spain was something of a non-event when it finally broke out, the breakdown of negotiations surrounding the Spanish Match did have the highly significant impact of driving England towards France in the European system of alliances.

虽然与西班牙的战争最终爆发时并不算什么大事，但围绕西班牙比赛的谈判破裂确实对推动英格兰在欧洲联盟体系中向法国靠拢产生了非常重大的影响。