六格骨牌（Hexomino），又称六连块，是一种多格骨牌，每块以六个全等的正方形连成，反射或旋转视作同一种共有三十五种，可以英文本母代表。

A hexomino (or 6-omino) is a polyomino of order 6, that is, a polygon in the plane made of 6 equal-sized squares connected edge-to-edge. The name of this type of figure is formed with the prefix hex(a)-. When rotations and reflections are not considered to be distinct shapes, there are 35 different Free hexominoes. When reflections are considered distinct, there are 60 one-sided hexominoes. When rotations are also considered distinct, there are 216 fixed hexominoes.