The mechanism of disease is largely mediated by inflammatory factors including hepcidin.
疾病的发病机制主要由炎症因子介导，如铁调素等。
Hepcidin
原声例句
Osmosis-血液肿瘤
Osmosis-血液肿瘤
Finally, IL-6 also works in the liver by increasing production of a molecule called hepcidin, which blocks further uptake of iron from the small intestine.
最后，白介素-6可通过增加一种叫做铁调素的分子在肝脏中起作用，这种分子可以进一步阻止小肠摄取铁。
中文百科
铁调素
铁调素（英语：Hepcidin）是一种由肝脏产生的肽类激素，发现于2000年，是人类和其它哺乳动物的铁离子代谢的主要调节者。
英语百科
Hepcidin 铁调素
Hepcidin is a protein that in humans is encoded by the HAMP gene. Hepcidin is a key regulator of the entry of iron into the circulation in mammals.
In states in which the hepcidin level is abnormally high such as inflammation, serum iron falls due to iron trapping within macrophages and liver cells and decreased gut iron absorption. This typically leads to anemia due to an inadequate amount of serum iron being available for developing red cells. When the hepcidin level is abnormally low such as in hemochromatosis, iron overload occurs due to decreased ferroportin mediated iron efflux.
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