汉福德区（英语：Hanford Site），位于美国华盛顿州哥伦比亚河畔汉福德镇，由美国联邦政府设置与管理，用来处理各种核能废料产物，是美国最大的放射性核废料处理厂区。这个地区有许多别名，例如汉福德计划（Hanford Project）、汉福德工厂（Hanford Works）、汉福德工程工厂（Hanford Engineer Works，HEW）或汉福德核能保存地（Hanford Nuclear Reservation，HNR）。它于1943年创建，最早是曼哈顿计划的一部份。在此地，兴建了B反应堆（B Reactor），是世界上第一个以钚运作的核反应堆。冷战期间，美国在此地建造核子武器。在冷战结束后，成为核能废料保存地。因为长期在此制造核能产品，曾经一度汉福德区成为美国遭核能污染最严重的厂区。现已经演变为美国能源部所属西北太平洋国家实验室。

The Hanford Site is a mostly decommissioned nuclear production complex operated by the United States federal government on the Columbia River in the U.S. state of Washington. The site has been known by many names, including: Hanford Project, Hanford Works, Hanford Engineer Works and Hanford Nuclear Reservation. Established in 1943 as part of the Manhattan Project in Hanford, south-central Washington, the site was home to the B Reactor, the first full-scale plutonium production reactor in the world. Plutonium manufactured at the site was used in the first nuclear bomb, tested at the Trinity site, and in Fat Man, the bomb detonated over Nagasaki, Japan.