Pantothenate kinase-associated neurodegeneration

（重定向自Hallervorden Spatz disease）

MRI image shows iron deposits in the basal ganglia, the so-called eye-of-the-tiger sign (T2w GRASE sequence).

Pantothenate kinase-associated neurodegeneration (PKAN), also known as neurodegeneration with brain iron accumulation 1 (NBIA1) and formerly called Hallervorden–Spatz syndrome (use of this eponym is somewhat discouraged due to Hallervorden and Spatz's affiliation with the Nazi regime and the ethically questionable manner in which they acted), is a degenerative disease of the brain that can lead to parkinsonism, dystonia, dementia, and ultimately death. Neurodegeneration in PKAN is accompanied by an excess of iron that progressively builds up in the brain.

单词	Hallervorden Spatz disease
释义	Hallervorden Spatz disease 英语百科 Pantothenate kinase-associated neurodegeneration （重定向自Hallervorden Spatz disease） Pantothenate kinase-associated neurodegeneration (PKAN), also known as neurodegeneration with brain iron accumulation 1 (NBIA1) and formerly called Hallervorden–Spatz syndrome (use of this eponym is somewhat discouraged due to Hallervorden and Spatz's affiliation with the Nazi regime and the ethically questionable manner in which they acted), is a degenerative disease of the brain that can lead to parkinsonism, dystonia, dementia, and ultimately death. Neurodegeneration in PKAN is accompanied by an excess of iron that progressively builds up in the brain.
随便看	a kick in the teeth的意思 a kick up the arse的意思 a kick up the backside的意思 a kid的意思 Akida的意思 akidogalvanocautery的意思 Akidograptus的意思 Akidogroptus的意思 akidopeirastic的意思 AKI的意思 Akieni的意思 Akifumi的意思 Akihabara的意思 Akiharu的意思 Akihiko的意思 Akihiro的意思 Akihisa的意思 Akihito的意思 Akihito的意思 Akiko的意思 akikoes的意思 Akil的意思 akila的意思 akilah的意思 Akili的意思