A signal triggers the pituitary gland to release the hormone gonadotropin.

这个信号会促使脑垂体释放出促性腺激素。

GnRH makes the nearby pituitary gland secrete two hormones of its own, called gonadotropins.

GnRH促使附近的垂体自身分泌两种激素，称为促性腺激素。

And that leads to low levels of the gonadotropin hormones, luteinizing and follicle-stimulating hormones, and low levels of gonadal function.

而这会导致促性腺激素（如促黄体生成素和卵泡刺激素水平）降低，以及性腺功能水平降低。

Over time, many ovarian follicles degenerate, and the ones that remain become less and less sensitive to gonadotropin stimulation.

随着时间的推移，许多卵巢卵泡退化，而余下的卵泡对促性腺激素的刺激变得越来越不敏感。

These are caused by overstimulation by human chorionic gonadotropin or hCG, a hormone that's produced by the placenta, so they're only seen in pregnancy.

这是由人体绒毛膜促性腺激素（hCG）过度刺激导致的；这种激素由胎盘释放，因此仅见于怀孕期间。

These gonadotropin hormones then stimulate the gonads to produce sex specific hormones.

这些促性腺激素随后刺激性腺生成性别特异性激素。

So, for example, a pinealoma may lead to increased secretion of the hormone beta human chorionic gonadotropin that can cause an early onset of puberty.

比如，松果体瘤可能导致β人绒毛膜促性腺激素分泌增加，可引起青春期发育提前。

High levels of cortisol also inhibit the secretion of gonadotropin- releasing hormone from the hypothalamus, which messes up normal ovarian and testicular function.

高水平皮质醇会抑制促性腺激素分泌，即下丘脑分泌的释放激素，导致卵巢和睾丸功能紊乱。

This goes on until menopause, when there are no remaining follicles responding to gonadotropins, and that causes menstruation and ovulation to cease entirely.

这种情况一直持续到绝经，此时没有剩余的卵泡对促性腺激素有反应；这导致月经和排卵完全停止。

Now, in premature ovarian failure, the follicles stop responding to gonadotropin stimulation earlier than usual - that being before the age of 40.

而在卵巢早衰患者中，卵泡更早停止对促性腺激素刺激的反应，即在40岁之前。