肝糖储积症（英语：Glycogen storage disease）属于一种合成、分解肝糖有缺陷的代谢疾病。另外，肝糖只分布于肝脏、肌肉。造成肝糖储积症的病症有两种，即先天与后天。先天型肝糖储积症是因为出生前代谢系统出现问题（例如有缺陷的酵素）；在家畜之中，后天型肝糖储积症是因为有毒的生物碱栗精胺所造成的。

整体而言，在不列颠哥伦比亚的调查显示，肝糖储积症发生率约为每10万名婴儿中会有2.3位，即每43000个婴儿中有1位；在美国的调查显示约20000至25000名婴儿中会有一人患有肝糖储积症；而在荷兰的发生率约为40000为婴儿中有1位。

Glycogen storage disease (GSD, also glycogenosis and dextrinosis) is the result of defects in the processing of glycogen synthesis or breakdown within muscles, liver, and other cell types.

GSD has two classes of cause: genetic and acquired. Genetic GSD is caused by any inborn error of metabolism (genetically defective enzymes) involved in these processes. In livestock, acquired GSD is caused by intoxication with the alkaloid castanospermine.