Now hemoglobin is made up of hemes and globins.

血红蛋白由血红素与珠蛋白构成。

Normally, hemoglobin is made up of four globin chains, each bound to a heme group.

正常情况下，血红蛋白由4条珠蛋白链组成，每条珠蛋白链都与一个血红素基团结合。

These four globin chains combine in different ways to give rise to different kinds of hemoglobin.

这四种珠蛋白链以不同的方式结合，形成不同类型的血红蛋白。

There are four globin subunits, typically two alpha and two beta, and each one has its own heme group.

它含有四个球蛋白亚基，通常是2个α亚基和2个β亚基，每个亚基都含有血红素分子。

There are 4 globin subunits, typically two alpha and two beta, and each one has its own heme group.

它有4个亚基，典型的为两个α亚基和两个β亚基，每一个都有对应的血红素。

Remember that the globin in your hemoglobin is a protein — and when proteins bind to stuff, they tend to change shape.

记住血红蛋白中的珠蛋白是一种蛋白质，当蛋白质和其他物质结合时它们就会改变形状。

This oxygen is bound to hemoglobin, which consists of an iron-containing pigment called heme and a protein part called globin.

这些氧气与血红蛋白结合，血红蛋白由叫做血红素的含铁的色素和叫做珠蛋白的蛋白质部分组成。

All right, as a quick recap: alpha thalassemia is an autosomal recessive disorder caused by deletion of alpha globin genes on chromosome 16.

得！快速回顾一下：α地中海贫血是一种常染色体隐性遗传病，由16号染色体上的α珠蛋白基因缺陷引起。