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单词 Gene regulation
释义

Gene regulation

原声例句
经济学人-科技

Drugs that demethylate DNA are under development, but are still some way from approval—and, in any case, interfering with epigenetics, which is a widespread mechanism of gene regulation, is a drastic approach.

让DNA反甲基化的药物还在研发中,并且还未通过临床证明。另外,外因遗传是基因调控的常见手段。从任何角度来说,干预外因遗传都是一种极端激进的做法。

经济学人 Science and technology

The unusual mechanism of gene regulation in C. elegans was assumed to be a peculiarity of that organism, not relevant to humans or other more complex organisms.

秀丽隐杆线虫中不寻常的基因调控机制被认为是该生物的特性,与人类或其他更复杂的生物无关。

经济学人 Science and technology

The joint winners were Victor Ambros at the University of Massachusetts Medical School and Gary Ruvkun at Massachusetts General Hospital for their discovery of micro-RNA (miRNA) and its role in " post-transcriptional gene regulation" .

共同获奖者为马萨诸塞大学医学院的维克多·安布罗斯 (Victor Ambros) 和马萨诸塞州总医院的加里·鲁夫昆 (Gary Ruvkun),以表彰他们发现微小核糖核酸 (miRNA) 及其在“转录后基因调控”中的作用。

英语百科

Regulation of gene expression

(重定向自Gene regulation)
Diagram showing at which stages in the DNA-mRNA-protein pathway expression can be controlled
1: RNA Polymerase, 2: Repressor, 3: Promoter, 4: Operator, 5: Lactose, 6: lacZ, 7: lacY, 8: lacA.
 Top: The gene is essentially turned off. There is no lactose to inhibit the repressor, so the repressor binds to the operator, which obstructs the RNA polymerase from binding to the promoter and making lactase. 
Bottom: The gene is turned on. Lactose is inhibiting the repressor, allowing the RNA polymerase to bind with the promoter, and express the genes, which synthesize lactase. Eventually, the lactase will digest all of the lactose, until there is none to bind to the repressor. The repressor will then bind to the operator, stopping the manufacture of lactase.

Regulation of gene expression includes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA), and is informally termed gene regulation. Sophisticated programs of gene expression are widely observed in biology, for example to trigger developmental pathways, respond to environmental stimuli, or adapt to new food sources. Virtually any step of gene expression can be modulated, from transcriptional initiation, to RNA processing, and to the post-translational modification of a protein. Often, one gene regulator controls another, and so on, in a gene regulatory network.

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更新时间:2025/6/22 5:42:31