基因银行（GenBank）是一个开放获取的串行数据库，对所有公开可利用的核苷酸串行与其翻译的蛋白质进行收集并注释。

此数据库是国际协作核酸串行数据库（INSDC）的一部分，由美国国家生物技术信息中心（NCBI）主管，NCBI为美国国立卫生研究院的下属机构。GenBank和它的合作者从全球各个实验室接收了超过百万种生物的数据。

成立三十年来，GenBank数据库成为了最重要的也是最有影响力的生物全领域数据库，其数据正被全球数以百万计的研究人员获取与引用。GenBank中的数据量正以每18个月翻一番的速度持续指数增长，在2013年2月的版本194中，数据库包含有1.62亿个串行，含有1500亿个核苷酸堿基。

The GenBank sequence database is an open access, annotated collection of all publicly available nucleotide sequences and their protein translations. This database is produced and maintained by the National Center for Biotechnology Information (NCBI) as part of the International Nucleotide Sequence Database Collaboration (INSDC). The National Center for Biotechnology Information is a part of the National Institutes of Health in the United States. GenBank and its collaborators receive sequences produced in laboratories throughout the world from more than 100,000 distinct organisms. In the more than 30 years since its establishment, GenBank has become the most important and most influential database for research in almost all biological fields, whose data are accessed and cited by millions of researchers around the world. GenBank continues to grow at an exponential rate, doubling every 18 months. Release 194, produced in February 2013, contained over 150 billion nucleotide bases in more than 162 million sequences. GenBank is built by direct submissions from individual laboratories, as well as from bulk submissions from large-scale sequencing centers.