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单词 Fourier Transform Mass Spectrometry
释义

Fourier Transform Mass Spectrometry

中文百科

傅里叶变换离子回旋共振质谱法 Fourier transform ion cyclotron resonance

(重定向自Fourier Transform Mass Spectrometry)
Linear ion trap - Fourier transform ion cyclotron resonance mass spectrometer (panels around magnet are missing).
A cylindrical ICR cell. The walls of the cell are made of copper, and ions enter the cell from the right, transmitted by the octopole ion guides.

傅里叶变换离子回旋共振质谱法也称作傅里叶变换质谱分析,这是一种根据给定磁场中的离子回旋频率来测量离子质荷比(m/z)的质谱分析方法。

彭宁离子阱(Penning Trap)中的离子被垂直于磁场的震荡电场激发出一个更大的回旋半径,这种激发作用同时也会导致离子的同相移动(形成离子束)。当回旋的离子束接近一对捕集板时,捕集板上会检测到影像电流信号。这种信号被称为自由感应衰减(FDI),是一种由许多重叠的正弦波组成的瞬态或干涉图。通过傅里叶变换,我们可以从这些信号数据中萃取出有用的信号形成质谱。

傅里叶变换离子回旋共振质谱法(FTICR-MS)具有非常高的析像能力,可以十分精确地测定物质。因此对于FTICR-MS的使用主要是利用它的高分辨率检测分子组成。这一检测的理论前提是元素在这一过程中会发生质量亏损。 此外,FTICR-MS通常也被用来研究复杂的混合物。这是由于它所产生的分析图像具有较窄的峰宽,能够将两个质量相近的离子返回的信号(质荷比m/z)区分开来。

英语百科

Fourier transform ion cyclotron resonance 傅里叶变换离子回旋共振质谱法

(重定向自Fourier Transform Mass Spectrometry)
Linear ion trap - Fourier transform ion cyclotron resonance mass spectrometer (panels around magnet are missing).
A cylindrical ICR cell. The walls of the cell are made of copper, and ions enter the cell from the right, transmitted by the octopole ion guides.

Fourier transform ion cyclotron resonance mass spectrometry is a type of mass analyzer (or mass spectrometer) for determining the mass-to-charge ratio (m/z) of ions based on the cyclotron frequency of the ions in a fixed magnetic field. The ions are trapped in a Penning trap (a magnetic field with electric trapping plates) where they are excited (at their resonant cyclotron frequencies) to a larger cyclotron radius by an oscillating electric field orthogonal to the magnetic field. After the excitation field is removed, the ions are rotating at their cyclotron frequency in phase (as a "packet" of ions). These ions induce a charge (detected as an image current) on a pair of electrodes as the packets of ions pass close to them. The resulting signal is called a free induction decay (FID), transient or interferogram that consists of a superposition of sine waves. The useful signal is extracted from this data by performing a Fourier transform to give a mass spectrum.

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更新时间:2025/6/23 14:02:02