Abstract: Foot-and-mouth disease (short for FMD), which is caused by foot-and-mouth disease virus (short for FMDV), is a zoonosis in artiodactyl.

口蹄疫是由口蹄疫病毒引起的主要侵害偶蹄类动物的一种人兽共患传染病。

The sequences and secondary structures of IRES are compared.Interaction between IRES and translation initiation factors and relation with virulence of FMDV is summarized.

本文对IRES的一、二级结构进行了比较，对IRES与翻译起始因子的相互作用以及对病毒毒力的影响作了综述。