Fecal bacteriotherapy

（重定向自Fecal transplant）

Escherichia coli at 10,000× magnification

A fecal microbiota transplant (FMT), also known as a stool transplant, is the process of transplantation of fecal bacteria from a healthy individual into a recipient. FMT involves restoration of the colonic microflora by introducing healthy bacterial flora through infusion of stool, e.g. by enema, orogastric tube or orally in the form of a capsule containing freeze-dried material, obtained from a healthy donor. A limited number of studies have shown it to be an effective treatment for patients suffering from Clostridium difficile infection (CDI), which can range from diarrhea to pseudomembranous colitis. Due to an epidemic of CDI in North America and Europe, FMT has gained increasing prominence, with some experts calling for it to become first-line therapy for CDI. In 2013 a randomized, controlled trial of FMT from healthy donors showed it to be highly effective in treating recurrent C. difficile in adults, and more effective than vancomycin alone. FMT has been used experimentally to treat other gastrointestinal diseases, including colitis, constipation, irritable bowel syndrome, and neurological conditions such as multiple sclerosis and Parkinson's. In the United States, the Food and Drug Administration (FDA) has regulated human feces as an experimental drug since 2013.

单词	Fecal transplant
释义	Fecal transplant 原声例句双语版 TED-Ed 演讲精选 So when symptoms get this bad, it's time for a fecal microbial transplant. 症状已经严重至此，就该进行粪菌移植了。科学60秒听力 2014年8月合集 All they needed was a fecal transplant, which supplied the necessary gut bacteria from their Mojave-based neighbors. 它们所需要的就是肠道细菌，这些必需菌将会由莫哈韦沙漠地区所居住的居民提供。双语版 TED-Ed 演讲精选 For example, fecal transplants from non-diabetic mice improved insulin resistance in mice with type 2 diabetes. 比如，来自未患有糖尿病小白鼠的粪菌移植改善了患有 2 型糖尿病的小白鼠的胰岛素抵抗情况。科学60秒-科学美国人 2022年4月合集 So it's not that you're putting something there that wasn't there, but it's really like this human fecal transplants. 这并不是把原本不在那的东西放过去，而是像人类粪便移植。 TED演讲（视频版） 2023年9月合集 Fecal transplants face various challenges to both effectiveness and acceptance. 粪便移植在有效性和接受度方面面临着各种挑战。双语版 TED-Ed 演讲精选 Because each stool sample is unique, the FDA still classifies fecal transplants as an experimental treatment rather than a formal medication. 由于每个粪便样本都是独特的，FDA 仍旧将粪菌移植划分为试验性治疗手段，而不是正规的药物治疗。双语版 TED-Ed 演讲精选 We still have a lot to learn about what makes the " best" gut microbiome, or the most beneficial fecal transplants. 我们还需要不断了解什么是“最好”的肠道菌群，或者最有益的粪菌移植。双语版 TED-Ed 演讲精选 But infusing a new batch of microorganisms into the intestine seems to help reset the gut microbiome — this is where fecal microbial transplants come into play. 但向肠道注入一批新的微生物似乎有助于重置肠道菌群——也就是粪菌移植的作用。双语版 TED-Ed 演讲精选 So currently, the US Food and Drug Administration only allows doctors to use fecal transplants experimentally for battling one of the toughest gut infections — antibiotic-resistant Clostridiodes difficile. 目前，美国食品药品监督管理局（FDA）只允许医生试验性地通过粪菌移植对付一种最严重的肠道感染疾病——耐抗生素梭状芽胞杆菌感染。 Asap SCIENCE 精选 This is why some scientists have suggested that treatment with probiotics or fecal transplants could be an effective therapy for overeating by getting rid of certain bacteria that generate intense cravings for high-fat and high-sugar foods. 这就是为什么一些科学家提出，益生菌或粪便移植治疗可以是有效治疗暴食的方法，就是通过去除那些会对高脂肪和高糖食物产生强烈渴望的细菌。 AsapSCIENCE - Health This is why some scientists have suggested that treatment with probiotics or fecal transplants could be an effective therapy for overeating; by getting rid of certain bacteria that generate intense cravings for high-fat and high-sugar foods. 这就是为什么一些科学家建议用益生菌或粪便移植治疗可以有效治疗暴饮暴食的原因；通过去除某些对高脂肪和高糖食物产生强烈渴望的细菌。英语百科 Fecal bacteriotherapy （重定向自Fecal transplant） A fecal microbiota transplant (FMT), also known as a stool transplant, is the process of transplantation of fecal bacteria from a healthy individual into a recipient. FMT involves restoration of the colonic microflora by introducing healthy bacterial flora through infusion of stool, e.g. by enema, orogastric tube or orally in the form of a capsule containing freeze-dried material, obtained from a healthy donor. A limited number of studies have shown it to be an effective treatment for patients suffering from Clostridium difficile infection (CDI), which can range from diarrhea to pseudomembranous colitis. Due to an epidemic of CDI in North America and Europe, FMT has gained increasing prominence, with some experts calling for it to become first-line therapy for CDI. In 2013 a randomized, controlled trial of FMT from healthy donors showed it to be highly effective in treating recurrent C. difficile in adults, and more effective than vancomycin alone. FMT has been used experimentally to treat other gastrointestinal diseases, including colitis, constipation, irritable bowel syndrome, and neurological conditions such as multiple sclerosis and Parkinson's. In the United States, the Food and Drug Administration (FDA) has regulated human feces as an experimental drug since 2013.
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