Steatosis

（重定向自Fatty degeneration）

Histological section of a mouse's liver showing severe steatosis. The clear vacuoles contained lipid in life; however, histological fixation caused it to be dissolved and hence only empty/clear spaces are seen.

Micrograph of fatty liver showing lipid steatosis. H&E stain.

Liver steatosis (fatty liver disease) as seen on CT

In cellular pathology, steatosis (also called fatty change, fatty degeneration or adipose degeneration) is the process describing the abnormal retention of lipids within a cell. It reflects an impairment of the normal processes of synthesis and elimination of triglyceride fat. Excess lipid accumulates in vesicles that displace the cytoplasm. When the vesicles are large enough to distort the nucleus, the condition is known as macrovesicular steatosis; otherwise, the condition is known as microvesicular steatosis. While not particularly detrimental to the cell in mild cases, large accumulations can disrupt cell constituents, and in severe cases the cell may even burst.

单词	Fatty degeneration
释义	Fatty degeneration 原声例句四季随笔 But set that possibility against the all but certainty of their present prospect — fatty degeneration of the soul; and is it not acceptable? 但是，将这种可能性与他们目前前景的几乎确定性相提并论——灵魂的脂肪退化；这是不可接受的吗？英语百科 Steatosis （重定向自Fatty degeneration） In cellular pathology, steatosis (also called fatty change, fatty degeneration or adipose degeneration) is the process describing the abnormal retention of lipids within a cell. It reflects an impairment of the normal processes of synthesis and elimination of triglyceride fat. Excess lipid accumulates in vesicles that displace the cytoplasm. When the vesicles are large enough to distort the nucleus, the condition is known as macrovesicular steatosis; otherwise, the condition is known as microvesicular steatosis. While not particularly detrimental to the cell in mild cases, large accumulations can disrupt cell constituents, and in severe cases the cell may even burst.
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