演化发育生物学（Evolutionary developmental biology、evo-devo）简称为演化发生学，是生物学的一个学门。探讨动物与植物等多细胞生物的发育过程，并由此研究不同个体之间的亲缘关系，以及发育过程的演化。

演化发生学是演化生物学与发育生物学的结合。演化生物学研究生物多样性的起源、现存物种与祖先物种的关系等，而演化发生学则是当代演化生物学家利用分子技术工具、基因组数据与比较基因组学等等资源，而能探讨基因与发育过程在演化史的改变、如何经过发育过程以塑造出特殊构造。在此领域中研究包含：生物特征的发育形成过程、发育可塑性在演化中的角色、生态的冲击如何造成发育与演化的改变、以及同源相似构造与异源相似构造的发育。

Evolutionary developmental biology (evolution of development or informally, evo-devo) is a field of biology that compares the developmental processes of different organisms to determine the ancestral relationship between them, and to discover how developmental processes evolved. It addresses the origin and evolution of embryonic development; how modifications of development and developmental processes lead to the production of novel features, such as the evolution of feathers; the role of developmental plasticity in evolution; how ecology impacts development and evolutionary change; and the developmental basis of homoplasy and homology.