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单词 Epidermal growth factor receptor
释义

Epidermal growth factor receptor

英语例句库

Objective: To observe affinity and tumoricidal power of monoclonal antibody EQ75 to epidermal growth factor receptor on glioma cells.

目的 观察同位素标记的抗表皮生长因子单克隆抗体EQ75对胶质瘤细胞的亲和力及杀伤力。

原声例句
Osmosis-消化

When proto-oncogenes, like epidermal growth factor receptor and RAS, are activated, it turns them into oncogenes that promote cell division.

当原癌基因(如表皮生长因子受体基因、RAS基因)被激活时,它们就变成了促进细胞分裂的癌基因。

Osmosis-生殖

Some breast cancers also have mutations in the ERBB2 gene that increase human epidermal growth factor receptor 2, or HER-2, which when activated, promotes the growth of cells.

一些乳腺癌也有ERBB2基因的突变,可以增加人表皮生长因子受体2(HER-2)的表达;当它HER-2被激活时,会促进细胞增长。

中文百科

表皮生长因子受体

EGFR信号传导级联

表皮生长因子受体英语:epidermal growth factor receptor,简称为EGFRErbB-1HER1)是一类名为表皮生长因子家族(EGF-家族)的细胞外蛋白配体的细胞表面受体 。

表皮生长因子受体是ErbB受体家族家族的成员之一,ErbB家族是包含四种紧密联系蛋白的亚家族,这四种蛋白分别是受体酪氨酸激酶类:EGFR(ErbB-1)HER2/c-neu(ErbB-2)、Her 3(ErbB-3)以及Her 4(ErbB-4)。影响EGFR表达或活性的突变可能导致癌症。

表皮生长因子及其受体是由范德堡大学的斯坦利·科恩发现的,科恩与丽塔·列维-蒙塔尔奇尼因发现生长因子类而共同获得了1986年诺贝尔生理学或医学奖。

英语百科

Epidermal growth factor receptor 表皮生长因子受体

EGFR signaling cascades
Diagram of the EGF receptor highlighting important domains

The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands.

The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.

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更新时间:2025/6/19 18:46:10