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单词 Epidermal growth factor
释义

Epidermal growth factor

英语例句库

Objective: To observe affinity and tumoricidal power of monoclonal antibody EQ75 to epidermal growth factor receptor on glioma cells.

目的 观察同位素标记的抗表皮生长因子单克隆抗体EQ75对胶质瘤细胞的亲和力及杀伤力。

原声例句
Osmosis-消化

When proto-oncogenes, like epidermal growth factor receptor and RAS, are activated, it turns them into oncogenes that promote cell division.

当原癌基因(如表皮生长因子受体基因、RAS基因)被激活时,它们就变成了促进细胞分裂的癌基因。

Osmosis-生殖

Some breast cancers also have mutations in the ERBB2 gene that increase human epidermal growth factor receptor 2, or HER-2, which when activated, promotes the growth of cells.

一些乳腺癌也有ERBB2基因的突变,可以增加人表皮生长因子受体2(HER-2)的表达;当它HER-2被激活时,会促进细胞增长。

中文百科

表皮生长因子

表皮生长因子(Epidermal growth factor,EGF)是最早发现的生长因子, 对调节细胞生长、 增殖和分化起着重要作用。在人类,表皮生长因子蛋白有53个氨基酸残基,三个二硫键,质量6千道耳顿。

表皮生长因子通过与细胞表面的受体表皮生长因子受体(EGFR)结合而起作用。与表皮生长因子受体的高亲和力结合,激发受体内在的酪氨酸激酶的活性,从而启动了信号传导级联而导致多种生物化学变化,细胞内钙水平上升, 增加糖酵解与蛋白质合成, 增加某些基因(包括表皮生长因子受体)的表达, 最终导致DNA合成和细胞增殖。

英语百科

Epidermal growth factor 表皮生长因子

Diagram showing key components of the MAPK/ERK pathway. In the diagram,

Epidermal growth factor (EGF) is a growth factor that stimulates cell growth, proliferation, and differentiation by binding to its receptor EGFR. Human EGF is a 6045-Da protein with 53 amino acid residues and three intramolecular disulfide bonds.

EGF was originally described independently as a secreted peptide found in the submaxillary glands of mice and in human urine. Initially, human EGF was known as urogastrone.

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更新时间:2025/6/19 13:39:27