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单词 Enzyme kinetics
释义

Enzyme kinetics

中文百科

酶动力学

来源于大肠杆菌的二氢叶酸还原酶 与它的两个底物,二氢叶酸(右)与和NADPH(左),两个底物包裹于活性位点之中。蛋白质用带状图来表示,其中α螺旋用红色表示,β折叠用黄色表示,而转角用蓝色表示。Generated from 7DFR.
反应速率将增加为底物浓度的增加,最终成为饱和在极高浓度的衬底。
Imagen generada por ordenador de un modelo de la estructura tridimensional de la enzima purina nucleósido fosforilasa bacteriana.
La velocidad de la reacción va aumentando a medida que aumenta la concentración de sustrato hasta que la enzima se satura.

酶动力学,又被称为酶催化动力学酶反应动力学酵素动力学,是研究酶催化的化学反应速率的学科。酶动力学对于某一特定酶的研究,可以提供许多重要信息。如该种酶的催化机理、在代谢途径中的作用、其在细胞中的活性如何被调控以及相关药物和毒药如何抑制其活性。

英语百科

Enzyme kinetics 酶动力学

Dihydrofolate reductase from E. coli with its two substrates dihydrofolate (right) and NADPH (left), bound in the active site. The protein is shown as a ribbon diagram, with alpha helices in red, beta sheets in yellow and loops in blue. Generated from 7DFR.
Progress curve for an enzyme reaction. The slope in the initial rate period is the initial rate of reaction v.  The Michaelis–Menten equation describes how this slope varies with the concentration of substrate.
A chemical reaction mechanism with or without enzyme catalysis. The enzyme (E) binds substrate (S) to produce product (P).Saturation curve for an enzyme reaction showing the relation between the substrate concentration and reaction rate.

Enzyme kinetics is the study of the chemical reactions that are catalysed by enzymes. In enzyme kinetics, the reaction rate is measured and the effects of varying the conditions of the reaction are investigated. Studying an enzyme's kinetics in this way can reveal the catalytic mechanism of this enzyme, its role in metabolism, how its activity is controlled, and how a drug or an agonist might inhibit the enzyme.

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更新时间:2025/6/17 0:40:14