Endiandric acid C



![Initial electrocyclizations in Nicolaou endiandric acid C synthesis, to provide diol 17 shown in the main scheme. This key intermediate is then ready for elaboration into the olefin which can undergo the further 6π[4+2] (Diels-Alder) cycloaddition reaction shown in the main scheme, to provide the title natural product.](/uploads/202501/11/ElectrocyclizationInEndrianicAcidSynth.svg4004.png)
Endiandric acid C, isolated from the Endiandra introrsa tree, is a well characterized chemical compound. Endiadric acid C is reported to have better antibiotic activity than ampicillin.
This genus of trees is in the family Lauraceae. These trees are found in the north-eastern Australian rainforests and other tropical and subtropical regions. However, these trees are also found in southern Canada and in Chile. Endiandric acid C is also isolated from E. xanthocarpa species. Endiandric acids are also found in Beilschmiedia trees, which were categorized under the Endiandra genus, but now forms its own genus as they found in cold, high latitude areas, and even in New Zealand. Other endiandric acids are found in the B. oligandra and B. anacardioides species, which are found in the Western Province of Cameroon.