君士坦丁堡普世牧首区（希腊语：Οἰκουμενικὸν Πατριαρχεῖον Κωνσταντινουπόλεως, Oikoumenikòn Patriarcheîon Konstantinoupóleos, 希腊语发音：[ikumenikˈon patriarˈxion konstantinuˈpoleos]）也称罗马牧首区（土耳其语：Rum Ortodoks Patrikhanesi），是东正教自主教会之一，最高领袖为君士坦丁堡普世牧首，现任牧首为巴塞洛缪一世。历史上曾经是东正教会首席大主教区。

The Ecumenical Patriarchate of Constantinople (Greek:Οικουμενικό Πατριαρχείο Κωνσταντινουπόλεως, Oikoumenikó Patriarkhío Konstantinoupóleos, IPA: [ikumenikˈon patriarˈxion konstantinuˈpoleos]; Latin:Patriarchatus Oecumenicus Constantinopolitanus; Turkish:Rum Ortodoks Patrikhanesi, "Roman Orthodox Patriarchate") is one of the fourteen autocephalous churches (or "jurisdictions") that together compose the Eastern Orthodox Church. It is headed by the Ecumenical Patriarch of Constantinople, currently Bartholomew I, Archbishop of Constantinople.