杜克斯县（The County of Dukes County）是美国麻萨诸塞州东南部的一个县，由玛莎葡萄园岛和伊莉莎伯群岛组成。面积1,272平方公里。根据美国2000年人口普查，共有人口14,987人。县治埃德加敦（Edgartown）。

1683年11月1日创建，原来是纽约省最早成立的十二个县之一，1691年10月7日转让予麻萨诸塞并从中分出南塔克特。县名纪念名义上的领主约克公爵。由于当时宪章定明本县「以杜克斯县命名」（by the name of Dukes County），因而形成了特别的写法。

The County of Dukes County is a county located in the U.S. state of Massachusetts. As of the 2010 census, the population was 16,535, making it the second-least populous county in Massachusetts. Its county seat is Edgartown.

Dukes County comprises the Vineyard Haven, MA Micropolitan Statistical Area. The county consists of the island of Martha's Vineyard, Chappaquiddick Island, the Elizabeth Islands (including Cuttyhunk) and other associated islets.